Cyclization by C(sp3)–H Arylation with a Transient Directing Group for the Diastereoselective Preparation of Indanes

Authors :: Erik J. Sorensen
Philip A. Provencher
John F. Hoskin
Katherine L. Bay
Kendall N. Houk
Jin-Quan Yu
Source :: ACS Catalysis. 11:3115-3127
Publication Year :: 2021
Publisher :: American Chemical Society (ACS), 2021.
Abstract: We report Pd(II)-catalyzed cyclative C(sp3)–H arylation of ketones with a transient directing group (TDG). Based on calculations, the oxidative addition step implicates a highly strained trigonal b...

Subjects :: 010405 organic chemistry
Indane
chemistry.chemical_element
General Chemistry
Trigonal crystal system
010402 general chemistry
01 natural sciences
Oxidative addition
Medicinal chemistry
Catalysis
0104 chemical sciences
chemistry.chemical_compound
chemistry
Group (periodic table)
Transient (oscillation)
Palladium

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