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A Multimodal Clinical Approach for the Treatment of Bone Metastases in Solid Tumors

Authors :
Giuliano Lo Bianco
Ezio Lanza
Salvatore Provenzano
Manuela Federico
Alfonso Papa
Farnad Imani
Gholamhosein Shirkhany
Riccardo Laudicella
Natale Quartuccio
Source :
Anesthesiology and Pain Medicine. 12
Publication Year :
2022
Publisher :
Briefland, 2022.

Abstract

Context: Bone metastasis (BM) is a frequent complication of cancer, representing the third most common site of secondary spread in solid cancers behind the lung and liver. Bone metastasis is found in up to 90% of prostate and breast cancer patients. They can cause significant complications, such as pathological fractures and paralysis of the spine, which decrease daily functioning and quality of life (QoL) and worsen prognosis. The growing life expectancy of cancer patients due to improvements in systemic therapies may further increase BM's eventuality and clinical burden in cancer patients. Evidence Acquisition: Four physicians from five different specialties were interviewed and resumed the most relevant literature of the last 20 years focusing on pain treatment in BM patients. Results: Treatment for BM ideally involves various types of specialists and assessments. The disease status and patient background should be considered, requiring holistic care and expertise from various medical specialties. Conclusions: Interventional, nuclear medicine, radiotherapy, and mini-invasive techniques can be safe and effective for relieving pain and modifying health-related QoL in BM patients.

Subjects

Subjects :
Anesthesiology and Pain Medicine

Details

ISSN :
22287531 and 22287523
Volume :
12
Database :
OpenAIRE
Journal :
Anesthesiology and Pain Medicine
Accession number :
edsair.doi...........99fb25a7abbd622abc6d8397c59936fe
Full Text :
https://doi.org/10.5812/aapm-126333