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46-YEAR-OLD MAN WITH A SPINAL CORD MASS
- Source :
- Brain Pathology. 21:109-112
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- Medulloblastoma accounts for only 1% of all adult CNS tumors. Likewise, recurrence of adult medulloblastoma greater than 20 years after initial diagnosis is extremely rare.We describe a case of adult medulloblastoma with late relapse of disease. The patient was 24 years old when first diagnosed and was treated with total tumor resection and craniospinal radiation. At the age of 45, an enhancing 1.3 cm intradural extramedullary spinal cord lesion at T5 was discovered on MRI. This was presumed to be recurrent medulloblastoma in the form of drop metastasis and the patient was treated with spinal radiation. Several months following treatment, at the age of 46, a follow-up MRI demonstrated an enhancing 1.4 cm intradural extramedullary spinal cord lesion at T7. The lesion was resected and histopathologic examination was most consistent with medulloblastoma, late drop metastasis. Although rare, adult medulloblastoma recurring 20 years after initial diagnosis should always be considered in the main differential diagnosis when working up CNS lesions at or outside the primary tumor site.
- Subjects :
- Medulloblastoma
medicine.medical_specialty
Adult Medulloblastoma
business.industry
General Neuroscience
Recurrent Medulloblastoma
medicine.disease
Spinal cord
Primary tumor
Pathology and Forensic Medicine
Lesion
medicine.anatomical_structure
Medicine
Neurology (clinical)
Radiology
Differential diagnosis
medicine.symptom
business
Craniospinal
Subjects
Details
- ISSN :
- 10156305
- Volume :
- 21
- Database :
- OpenAIRE
- Journal :
- Brain Pathology
- Accession number :
- edsair.doi...........9997fdd487297465d79bb819698ff2de
- Full Text :
- https://doi.org/10.1111/j.1750-3639.2010.00451.x