Somatic copy number abnormalities (SCNAs) and mutations in PI3K/AKT pathway as prognostic factors for overall survival (OS) in platinum-treated locally advanced or metastatic urothelial tumors

Authors :: Lillian Werner
Markus Riester
Jonathan E. Rosenberg
Paul Van Hummelen
Joaquim Bellmunt
Jeffrey J. Leow
Stephanie A. Mullane
Source :: Journal of Clinical Oncology. 32:4511-4511
Publication Year :: 2014
Publisher :: American Society of Clinical Oncology (ASCO), 2014.
Abstract: 4511 Background: An integrative analysis was conducted to identify genomic alterations and mutational status on the gene pathway level that could predict OS in pts with urothelial cancers (UC) trea...

Subjects :: Cancer Research
Oncology
business.industry
Somatic cell
Cancer research
Overall survival
Locally advanced
Mutational status
Medicine
Bioinformatics
business
PI3K/AKT/mTOR pathway
Gene pathway

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