Nanoemulgel: a promising novel formulation for treatment of skin ailments

Nanoemulgel is an emanating drug delivery system particularly being explored in research and development of various topical formulations for both pharmaceutical and cosmeceutical applications. Nanoemulgel consists of emulsion, which can be water in oil or oil in water type, incorporated into gel base. The gel base is prepared using gelling agent which modifies emulsion into non-greasy, more stable, and viscous formulation. Incorporation of hydrophobic drugs in a topical gel formulation along with favorable patient compliance is not feasible, but nanoemulgel form of the same drug does that efficiently. Rationalized formulation development of nanoemulgel for various drugs could solve various problems related to drug solubility, stability and drug release associated with other topical formulations.