Antihyperglycemic, Antihyperlipidemic and Antioxidant Effects of Eclipta prostrata L. Aqueous Extract in Streptozotocin-Induced Diabetic Rats

With the rising prevalence of diabetes mellitus around the world, researchers have been searching for a new treatment option that is both more effective and safer than chemotherapy. This study evaluated the antidiabetic activities of aqueous extracts of Eclipta prostrataL. in streptozotocin (STZ)-induced diabetic rats. The rats were randomized into six groups: Normal control, STZ-induced diabetic rats (50 mg/kg), STZ + EPE (100 mg/kg), STZ + EPE (200 mg/kg), STZ+glibenclamide (600 µg/kg) and EPE alone (200 mg/kg). The STZ-induced diabetic rats showed significantly (p