Mismatch repair deficiency testing for immune checkpoint therapy: Immunohistochemistry vs microsatellite instability

Authors :: Vladislav Chizhevsky
Forrest Blocker
Josette William Ragheb
Vincent Funari
Maher Albitar
Sally Agersborg
Wayne Chen
Shiping Jiang
Sucha Sudarsanam
Source :: Journal of Clinical Oncology. 36:3022-3022
Publication Year :: 2018
Publisher :: American Society of Clinical Oncology (ASCO), 2018.
Abstract: 3022Background: DNA mismatch repair deficiency (dMMR) can be tested by immunohistochemistry (IHC) or microsatellite instability (MSI). While either IHC and MSI is adequate for establishing Lynch sy...

Subjects :: congenital, hereditary, and neonatal diseases and abnormalities
Cancer Research
business.industry
food and beverages
nutritional and metabolic diseases
Microsatellite instability
medicine.disease
digestive system diseases
Immune checkpoint
Oncology
Cancer research
MISMATCH REPAIR DEFICIENCY
Medicine
Immunohistochemistry
DNA mismatch repair
business
neoplasms

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