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ChemInform Abstract: Potent Cyclic Urea HIV Protease Inhibitors with Benzofused Heterocycles as P2/P2′ Groups

Authors :
James D. Rodgers
M. M. Rayner
Gilbert N. Lam
Haisheng Wang
Chong-Hwan Chang
Barry L. Johnson
Beverly C. Cordova
Ronald M. Klabe
Susan Erickson-Viitanen
Roger A. Greenberg
Source :
ChemInform. 28
Publication Year :
2010
Publisher :
Wiley, 2010.

Abstract

A series of benzofused heterocycles was examined to replace the metabolically unstable benzyl alcohol P2/P2′ groups of DMP 323 (1). Extremely potent inhibitors of HIV protease (Ki

Details

ISSN :
09317597
Volume :
28
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........9877baec8f75bfb79bfdd7636c51c094
Full Text :
https://doi.org/10.1002/chin.199723196