Response to Ward

We read with interest the comments of Ward (1) on our microdialysis-based continuous glucose monitoring system. We especially appreciate that he shares our delight on the stability (i.e., lack of time-dependent signal decline) of this system, which has been verified by standardized regression analysis. Furthermore, Ward raises the important general question of the optimal way to evaluate a continuous glucose monitoring device—an open question so far. Our suggestion is to perform an evaluation of a continuous glucose monitoring device in a stepwise approach consisting of a …