Back to Search
Start Over
Plasma carotenoids, retinol and tocopherol levels and the risk of ovarian cancer
- Source :
- Acta Obstetricia et Gynecologica Scandinavica. 88:457-462
- Publication Year :
- 2009
- Publisher :
- Wiley, 2009.
-
Abstract
- Objective. We investigated the relation between plasma carotenoids, retinol and tocopherol levels and ovarian cancer risk in Korean women. Design. Hospital-based case–control study. Setting. Six tertiary medical institutes in Korea. Population. Forty-five epithelial ovarian cancers and 135 age-matched controls. Methods. Preoperative plasma concentrations of β-carotene, lycopene, zeaxanthin plus lutein, retinol, α-tocopherol, and γ-tocopherol were measured by reverse-phase, gradient high-pressure liquid chromatography. Main outcome measures. Odds ratios (OR) and 95% confidence intervals (95%CI) were estimated by tertiles to evaluate the effect of micronutrients on endometrial cancer risk after adjustment for body mass (BMI) index, menopause, parity, oral contraceptive use, smoking status, and alcohol consumption status. Results. Women in the highest tertile for β-carotene had 0.12-times the risk of ovarian cancer of in the lowest tertile (OR 0.12; 95%CI 0.04–0.36). Women with the highest tertiles of lycope...
- Subjects :
- Gynecology
medicine.medical_specialty
education.field_of_study
business.industry
Endometrial cancer
Population
Retinol
Obstetrics and Gynecology
Cancer
Physiology
General Medicine
Odds ratio
medicine.disease
Menopause
chemistry.chemical_compound
chemistry
medicine
Risk factor
Ovarian cancer
business
education
Subjects
Details
- ISSN :
- 16000412 and 00016349
- Volume :
- 88
- Database :
- OpenAIRE
- Journal :
- Acta Obstetricia et Gynecologica Scandinavica
- Accession number :
- edsair.doi...........97ff51d86a57de31c74c427dff65097e