Electrochemical 3D printed silver nanoparticles for pharmaceutical drugs investigations

Quick detection of pharmaceutical drugs, such as paracetamol, pantoprazole sodium, and diclofenac sodium, by localized surface plasmon resonance (LSPR) Raman using novel meniscus confined electrochemical additive manufacturing (ECAM) printed silver nanoparticle substrate is studied. The ECAM printing process produced pure phase silver substrates without any impurity, and the quality of the electro-deposited substrates is analyzed by optical and scanning electron microscopy. The electro-deposited nanoparticle substrate has average crystallite and particle size 18 nm and 60 nm respectively. The LSPR Raman spectra show up to four times enhancement in the original Raman signals.