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An electrochemical enzyme-free glucose sensor based on bimetallic PtNi materials

Authors :
Fang Liu
Mei Wang
Dongdong Chen
Source :
Journal of Materials Science: Materials in Electronics. 32:23445-23456
Publication Year :
2021
Publisher :
Springer Science and Business Media LLC, 2021.

Abstract

This paper investigates a novel electrochemical enzyme-free glucose sensor based on bimetallic PtNi materials. Pt and Ni layer were sputtered on the substrate and then annealed to form bimetallic PtNi materials, which served as sensitive materials for glucose detection. The effect of annealing temperature on the performance of enzyme-free glucose sensors had been studied deeply. Using micro-electromechanical systems (MEMS) technology, a monolithic enzyme-free glucose sensor was fabricated, which integrated with working electrode (WE) and counter electrode (CE) on a chip. The electrochemical results demonstrate that the device exhibits outstanding sensitivity and selectivity for glucose detection, achieving a maximal sensitivity of 1618.15 µA mM−1 cm−2 in the range of 0–10 mM with a low detection limit of 8.76 µM. The sensor also shows its practical application for glucose detection in human blood serum. Due to its performance and fabrication process, the enzyme-free glucose sensor is therefore well suited for glucose detection and manufacture together with other integrated circuits on a single silicon wafer, which shows potentials in implantable microelectronic systems.

Details

ISSN :
1573482X and 09574522
Volume :
32
Database :
OpenAIRE
Journal :
Journal of Materials Science: Materials in Electronics
Accession number :
edsair.doi...........96fabbab074087996149afb2d7cd4780
Full Text :
https://doi.org/10.1007/s10854-021-06832-3