Acquired spherocytic like anemia combined with ineffective erythropoiesis sustains anemia in patients with chronic hepatitis C infection receiving telaprevir or boceprevir-based triple therapy

s / Digestive and Liver Disease 47S (2015) e1–e18 e15 replication, in its presence the inhibition exerted by 17 -estradiol was reverted in a dose-dependent manner. Conclusions: In vitro, 17 -estradiol is able to block HCV infection, likely by modulation of intracellular pathways following binding to the estradiol receptor, whose activation leads to an antiviral state. http://dx.doi.org/10.1016/j.dld.2015.01.034