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ChemInform Abstract: An Atom-Economic Synthesis of Functionalized Pyrroles via a Sequential Metal-Catalyzed Three-Component Reaction

ChemInform Abstract: An Atom-Economic Synthesis of Functionalized Pyrroles via a Sequential Metal-Catalyzed Three-Component Reaction

Authors :
Gu Jiachao
Wu Zhengguang
Wang Xinglong
Bu Hongzhong
Li Yufeng
Ma Hongfei
Wu Xiaowei
Shi Jie
Source :
ChemInform. 45
Publication Year :
2014
Publisher :
Wiley, 2014.

Abstract

A three-component reaction of one molecule of imine and two molecules of alkynoates is realized with the catalysis of Cu(I)–Fe(III) in a sequential manner to allow the direct synthesis of functionalized pyrroles, during which, one C–N bond and two C–C bonds are formed with high atom economy. This method benefits from easily available starting materials, low-cost catalysts, and convenient operations.

Details

ISSN :
09317597
Volume :
45
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........9675804d94c7571a2d215d0dd66b72c2
Full Text :
https://doi.org/10.1002/chin.201434137