O009 Completion of supervised exercise therapy improves outcomes for patients with intermittent claudication: propensity score-matched analysis of 7-year outcomes

Introduction The goal of this study was to compare the long-term outcomes of patients with intermittent claudication (IC) who completed supervised exercise therapy (SET) versus patients who either declined or prematurely discontinued SET. Methods A retrospective, observational, single-centre cohort study of patients with IC referred to SET. Outcomes included progression to chronic limb-threatening ischemia (CLTI), revascularization requirement, and cardiovascular death.1:1 propensity score matching (PSM) using nearest-neighbour (caliper=0.2) was performed. Multivariate analysis (MVA) and logistic-regression (LR) were used to identify significant effect modifiers to guide PSM. Time-to-event data were analysed using Kaplan-Meier survival analysis. Results 241 patients were referred to SET between July 2015 and July 2016. Forty-nine patients completed SET and 192 patients did not. There was no significant difference in age, diabetes, smoking-cessation, and medication compliance between groups. After PSM, 49 patients who declined SET and 41 patients who completed SET were analysed. Progression to CLTI was significantly lower (10.2% vs 65.9%; p Conclusion SET for claudication reduces requirement for future revascularisation by slowing disease progression.