ChemInform Abstract: Iridium-Catalyzed Coupling Reaction of Primary Alcohols with 1-Aryl-1-propynes Leading to Secondary Homoallylic Alcohols

Authors :: Yasutaka Ishii
Shintaro Hatanaka
Yasushi Obora
Source :: ChemInform. 40
Publication Year :: 2009
Publisher :: Wiley, 2009.
Abstract: We report iridium-catalyzed coupling of 2-alkynes such as 1-aryl-1-propynes with primary alcohols leading to secondary homoallylic alcohols as products. This reaction involves an iridium-catalyzed novel catalytic transformation of 2-alkynes and primary alcohols through the formation of hydrido(π-allyl)iridium as a possible key intermediate.

Subjects :: Catalytic transformation
chemistry.chemical_compound
Primary (chemistry)
chemistry
Aryl
chemistry.chemical_element
General Medicine
Iridium
Medicinal chemistry
Coupling reaction
Catalysis

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