SYNTHESIS OF SOME NEW QUINOLINE DERIVATIVES OF POTENTIAL ANTIMICROBIAL ACTIVITY

Authors :: Kamel Metwally
Sobhy M. El-Adl
Mansour Abou-Kull
El-Sayed M. Lashine
Source :: Zagazig Journal of Pharmaceutical Sciences. 8:23-27
Publication Year :: 1999
Publisher :: Egypts Presidential Specialized Council for Education and Scientific Research, 1999.
Abstract: A series of quinolinoxymethyl triazole (5), oxadiazole (6,8), isoxazolidin-3,5-diones (10), pyrazolidin-3,5-diones (11a,b) and other related pyrimidin-2,4,6-triones (12,) and pyrimidin-4,6-dione-2-thiones (12a) were synthesized. Four of the synthesized compounds were tested for antimicrobial activity; two of them displayed high activity against a variety of bacterial strains.