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A mild procedure for the clay catalyzed selective removal of the tert-butoxycarbonyl protecting group from aromatic amines
- Source :
- Tetrahedron Letters. 41:385-387
- Publication Year :
- 2000
- Publisher :
- Elsevier BV, 2000.
-
Abstract
- The application of solid acidic catalysts for the selective removal of N-Boc protection is presented in this report. Montmorillonite K10 was found to be an effective catalyst in removing aromatic N-Boc groups while leaving aliphatic N-Boc amines untouched.
Details
- ISSN :
- 00404039
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Tetrahedron Letters
- Accession number :
- edsair.doi...........9417a5922f94e9c669a725e9c6d410cd
- Full Text :
- https://doi.org/10.1016/s0040-4039(99)02028-6