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A hydrophobic core sequence of anti‐apoptotic protein Bcl‐2 inserts into a model membrane in an α helical conformation

Authors :
Suzanne M. Lapolla
Olga Nikolaeva
Jialing Lin
Source :
The FASEB Journal. 20
Publication Year :
2006
Publisher :
Wiley, 2006.

Abstract

Bcl-2 family proteins are critical regulators of apoptosis and function at the level of mitochondria and endoplasmic reticulum. Bcl-2 is a tail-anchored protein in the membranes, but its cytosolic ...

Details

ISSN :
15306860 and 08926638
Volume :
20
Database :
OpenAIRE
Journal :
The FASEB Journal
Accession number :
edsair.doi...........933c9d43e5bb940387a5d1ac993a417a
Full Text :
https://doi.org/10.1096/fasebj.20.4.a121-c