Inhibition of the Sonic Hedgehog Pathway by Cyclopamine or GLI1 siRNA Reduces In Vivo Tumorigenesis of Human Medulloblastoma Cells Xenotransplanted to Immunodeficient Nude Mice

Authors :: Bárbara Meléndez
Paula Schiapparelli
Mónica Enguita-Germán
Javier de la Rosa
Mehdi H. Shahi
Juan A. Rey
Ricardo García-López
Miguel Angel Idoate
Javier S. Castresana
Mónica Sánchez
Source :: Advances in Translational Medicine Research. 1
Publication Year :: 2019
Publisher :: sPage.direcT, 2019.

Subjects :: Medulloblastoma
Cyclopamine
biology
Chemistry
medicine.disease
medicine.disease_cause
Hedgehog signaling pathway
chemistry.chemical_compound
In vivo
GLI1
medicine
Cancer research
biology.protein
Carcinogenesis

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