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Biocatalytic reduction of a racemic selenocyclohexanone by Brazilian basidiomycetes
- Source :
- Tetrahedron: Asymmetry. 18:1398-1402
- Publication Year :
- 2007
- Publisher :
- Elsevier BV, 2007.
-
Abstract
- An efficient synthesis of the chiral cyclic secondary alcohols, trans -2-(phenylseleno)cyclohexanol 1a and cis -2-(phenylseleno)cyclohexanol 1a , was obtained by enzymatic reduction of 2-(phenylseleno)cyclohexanone 1 using whole fungal cells. Five strains of white-rot basidiomycetes were examined; Irpex lacteus CCB 196, Pycnoporus sanguineus CCB 196, Trametes rigida CCB 285, Trametes versicolor CCB 202 and Trichaptum byssogenum CCB 203. Cells of T. rigida CCB 285 gave alcohols cis -( RS )- 1a and trans -( SS )- 1a in high enantiomeric excesses (ca. 99%).
- Subjects :
- biology
Stereochemistry
Chemistry
Organic Chemistry
Cyclohexanol
Irpex lacteus
Cyclohexanone
biology.organism_classification
Catalysis
Inorganic Chemistry
chemistry.chemical_compound
Trametes
Trichaptum byssogenum
Physical and Theoretical Chemistry
Enantiomer
Pycnoporus sanguineus
Trametes versicolor
Subjects
Details
- ISSN :
- 09574166
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Tetrahedron: Asymmetry
- Accession number :
- edsair.doi...........92635dac7a3cdcfa9df0748ead2e2b0d
- Full Text :
- https://doi.org/10.1016/j.tetasy.2007.05.036