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Synthesis of 1α,25-dihydroxy-22-thiavitamin D3 and related analogs

Authors :
Noboru Kubodera
Akira Kawase
Koichi Endo
Michinori Hirata
Source :
Bioorganic & Medicinal Chemistry Letters. 5:279-282
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

The 22-thiolation reaction of the steroidal side chain and the synthesis of 1α,25-dihydroxy-22-thiavitamin D3 and related analogs bearing side chains of different sizes in combination with 20-epi configuration are described.

Details

ISSN :
0960894X
Volume :
5
Database :
OpenAIRE
Journal :
Bioorganic & Medicinal Chemistry Letters
Accession number :
edsair.doi...........91ea8d8af21c635d6655287d21362e2d
Full Text :
https://doi.org/10.1016/0960-894x(95)00015-l