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Protective effect of astragalin and quercetin on ultraviolet (UV)-irradiated damage in HaCaT cells and Balb/c mice
- Source :
- Journal of the Korean Society for Applied Biological Chemistry. 55:443-446
- Publication Year :
- 2012
- Publisher :
- Springer Science and Business Media LLC, 2012.
-
Abstract
- Co-treatment of astragalin and quercetin (AGQC) significantly suppressed the ultraviolet (UV)-induced keratinocyte damage. Administration of AGQC in UV-irradiated mice reduced the histological skin alterations and the levels of chemokine (C-X-C motif) ligand 1 (CXCL1) and CXCL2. These results suggest that AGQC has a potential use as a compound for protection against UV-irradiated skin damage.
- Subjects :
- Chemokine
integumentary system
biology
Organic Chemistry
biology.organism_classification
Molecular biology
General Biochemistry, Genetics and Molecular Biology
BALB/c
CXCL1
HaCaT
CXCL2
chemistry.chemical_compound
medicine.anatomical_structure
chemistry
biology.protein
medicine
Astragalin
Keratinocyte
Quercetin
Subjects
Details
- ISSN :
- 2234344X and 17382203
- Volume :
- 55
- Database :
- OpenAIRE
- Journal :
- Journal of the Korean Society for Applied Biological Chemistry
- Accession number :
- edsair.doi...........9139856bbc6771d068e1c1f6c52d506f