ChemInform Abstract: A Rapid and Divergent Access to Chiral Azacyclic Nucleoside Analogues via Highly Enantioselective 1,3-Dipolar Cycloaddition of β-Nucleobase Substituted Acrylates

Authors :: Hai-Ming Guo
Huan-Li Sun
Gui-Rong Qu
Qi-Liang Yang
Zhen Guo
Dan-Jie Zhang
Ming-Sheng Xie
Ke-Xin Huang
Chao Xia
Source :: ChemInform. 46
Publication Year :: 2015
Publisher :: Wiley, 2015.
Abstract: A novel protocol for an asymmetric 1,3-dipolar cycloaddition of azomethine ylides with β-nucleobase acrylates gives access to chiral azacyclic nucleosides.

Subjects :: Stereochemistry
Chemistry
1,3-Dipolar cycloaddition
Nucleic acid
Enantioselective synthesis
General Medicine
Nucleoside
Cycloaddition
Nucleobase

Full Text Access

Tools