Inhibitory effect of strongly acid polypeptides on repair of double-stranded DNA breaks induced by ?-irradiation in Chinese hamster fibroblast's

The morphology peculiarities of thymus epithelial canals of 120 Wistar-line rats with thymosin have been observed. Thymosin-5 introduction during 3 days after birth in the dosage of 50 g proved to eliminate the epithelial canals of rat thymus in 3, 7 days of the postnatal period. In this period the epithelial canals have been found in thymus of all intact and control physiological solution injected rats. In 14, 30 days after birth the epithelial canals in experimental rats are found more often than in control ones. Thus, for the first time the evidence of thymosin-dependent characteristics of thymus epithelial canals has been obtained. The possible influence of epithelial canals on the regulation of T-forerunners entrance thymus has been discussed.