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PTP4A3, a Signal Molecule Deregulated in Uveal Melanoma Metastasis
- Source :
- Signal Transduction in Cancer Metastasis ISBN: 9789048195213
- Publication Year :
- 2010
- Publisher :
- Springer Netherlands, 2010.
-
Abstract
- Despite improvements in primary treatment protocols, more than 50% of the patients with uveal melanoma die of late-occurring metastases located in the liver. After diagnosis of metastases the average life expectancy is 6 months and no effective treatment is available at this stage of the disease. Transcriptome analysis linked to comparative genomic hybridization have been used for this particular melanoma to identify a set of genes linked to metastasis that may represent valuable future targets for specific treatments.
Details
- ISBN :
- 978-90-481-9521-3
- ISBNs :
- 9789048195213
- Database :
- OpenAIRE
- Journal :
- Signal Transduction in Cancer Metastasis ISBN: 9789048195213
- Accession number :
- edsair.doi...........90bd5e456c590c334a3a524c0ab7a054