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Has It Really Been Demonstrated That Most Genomic Research Findings Are False?

Authors :
Gregory P. Samsa
Source :
The American Statistician. 69:1-4
Publication Year :
2015
Publisher :
Informa UK Limited, 2015.

Abstract

In a widely cited article, Ioannidis argued that most published research findings are false; particularly discovery research involving massive testing, genomics being a typical example. However, his argument ignores adjustment for multiple testing and thus should be taken with a large grain of salt. This is a potential example for statistics courses that concentrate on problem formulation.

Details

ISSN :
15372731 and 00031305
Volume :
69
Database :
OpenAIRE
Journal :
The American Statistician
Accession number :
edsair.doi...........90b842a2b879206d2bf5399363971aa2
Full Text :
https://doi.org/10.1080/00031305.2014.951127