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Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns of relapse

Authors :
Morie A. Gertz
Prashant Kapoor
Francis K. Buadi
David Dingli
Surbhi Sidana
Suzanne R. Hayman
Angela Dispenzieri
Wilson I. Gonsalves
S. Vincent Rajkumar
Ronald S. Go
Rahma Warsame
Amie Fonder
Taxiarchis Kourelis
Shaji Kumar
Robert A. Kyle
Nelson Leung
Yi Lisa Hwa
Miriam Hobbs
Nidhi Tandon
Martha Q. Lacy
Source :
Leukemia. 33:730-738
Publication Year :
2018
Publisher :
Springer Science and Business Media LLC, 2018.

Abstract

Achieving a complete response (CR) is associated with improved overall survival (OS) in multiple myeloma (MM), but data on duration of CR (DurCR) are limited. We evaluated 351 patients (2004–2016), achieving CR with first-line therapy. Patients with sustained DurCR ≥ 24 months (n = 177) had better OS; 150 vs. 81 months, p

Details

ISSN :
14765551 and 08876924
Volume :
33
Database :
OpenAIRE
Journal :
Leukemia
Accession number :
edsair.doi...........8fcef9d3592718929dda8fc9808dd8fc