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Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns of relapse
- Source :
- Leukemia. 33:730-738
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- Achieving a complete response (CR) is associated with improved overall survival (OS) in multiple myeloma (MM), but data on duration of CR (DurCR) are limited. We evaluated 351 patients (2004–2016), achieving CR with first-line therapy. Patients with sustained DurCR ≥ 24 months (n = 177) had better OS; 150 vs. 81 months, p
- Subjects :
- 0301 basic medicine
Immunofixation
Cancer Research
medicine.medical_specialty
biology
business.industry
Hematology
Newly diagnosed
medicine.disease
Gastroenterology
03 medical and health sciences
030104 developmental biology
0302 clinical medicine
Oncology
Maintenance therapy
030220 oncology & carcinogenesis
Internal medicine
medicine
biology.protein
Biochemical relapse
Monoclonal protein
Stage (cooking)
business
Multiple myeloma
Complete response
Subjects
Details
- ISSN :
- 14765551 and 08876924
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Leukemia
- Accession number :
- edsair.doi...........8fcef9d3592718929dda8fc9808dd8fc