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Dietary fiber intake and fecal short-chain fatty acid concentrations are associated with lower plasma lipopolysaccharide-binding protein and inflammation

Authors :
Melisa A. Bailey
Sharon V. Thompson
Annemarie R. Mysonhimer
Jessica N. Bennett
James J. Vanhie
Michael De Lisio
Nicholas A. Burd
Naiman A. Khan
Hannah D. Holscher
Source :
American Journal of Physiology-Gastrointestinal and Liver Physiology. 324:G369-G377
Publication Year :
2023
Publisher :
American Physiological Society, 2023.

Abstract

Dietary fiber intake may reduce the inflammation associated with obesity and metabolic disease. Our cross-sectional analysis revealed that dietary fiber intake and fecal short-chain fatty acids are inversely associated with lipopolysaccharide-binding protein, a marker of systemic inflammation. In addition, plasma interleukin-6 and C-reactive protein were positively related to markers of adiposity.

Details

ISSN :
15221547 and 01931857
Volume :
324
Database :
OpenAIRE
Journal :
American Journal of Physiology-Gastrointestinal and Liver Physiology
Accession number :
edsair.doi...........8f5a74d534ed10c95647172847826a8c
Full Text :
https://doi.org/10.1152/ajpgi.00176.2021