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Risk Factors for Frailty and Cardiovascular Diseases: Are They the Same?
- Source :
- Advances in Experimental Medicine and Biology ISBN: 9783030333294
- Publication Year :
- 2020
- Publisher :
- Springer International Publishing, 2020.
-
Abstract
- Cardiovascular disease burden increases with the increasing age of populations. Also, with increasing longevity, some individuals are ageing along an unfavourable path developing frailty syndrome. Epidemiologic studies indicate that frailty is overrepresented among the persons with cardiovascular disease. On the other hand, frail subjects tend to be burdened with cardiovascular disease to a greater degree than their biologically better-off peers. Hypertension, diabetes, and obesity, especially abdominal, and at least some other risk factors appear to be shared between frailty and cardiovascular disease. The probable common underlying pathophysiologic feature is inflammation and associated phenomena, possibly having its root in the inflammageing. We discuss these issues based on the results of original studies, comprehensive literature reviews, and metaanalyses, by hundreds of dedicated researchers worldwide.
- Subjects :
- Gerontology
medicine.medical_specialty
business.industry
media_common.quotation_subject
Frailty syndrome
Longevity
Disease
medicine.disease
Obesity
03 medical and health sciences
0302 clinical medicine
Ageing
Diabetes mellitus
Epidemiology
medicine
030212 general & internal medicine
business
Disease burden
media_common
Subjects
Details
- ISBN :
- 978-3-030-33329-4
- ISBNs :
- 9783030333294
- Database :
- OpenAIRE
- Journal :
- Advances in Experimental Medicine and Biology ISBN: 9783030333294
- Accession number :
- edsair.doi...........8db4b10c2f1dd47e2a5623ad34e6c34d