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Steroidal Glycosides from Furcraea foetida and Their Cytotoxic Activity
- Source :
- CHEMICAL & PHARMACEUTICAL BULLETIN. 57:1161-1166
- Publication Year :
- 2009
- Publisher :
- Pharmaceutical Society of Japan, 2009.
-
Abstract
- Two new spirostanol glycosides (1, 2) and a new furostanol glycoside (3), together with nine known steroidal glycosides (4-12) were isolated from the leaves of Furcraea foetida (Agavaceae). The structures of the new compounds were determined by spectroscopic analysis and the results of hydrolytic cleavage. The isolated compounds were evaluated for their cytotoxic activities against HL-60 human leukemia cells, A549 human lung adenocarcinoma cells, HSC-2 human oral squamous carcinoma cells, and HSC-4 human oral squamous carcinoma cells.
- Subjects :
- chemistry.chemical_classification
biology
Traditional medicine
Chemistry
Glycoside
General Chemistry
General Medicine
medicine.disease
biology.organism_classification
Squamous carcinoma
Biochemistry
Cell culture
Drug Discovery
medicine
Adenocarcinoma
Furcraea
Cytotoxic T cell
Cytotoxicity
Medicinal plants
Subjects
Details
- ISSN :
- 13475223 and 00092363
- Volume :
- 57
- Database :
- OpenAIRE
- Journal :
- CHEMICAL & PHARMACEUTICAL BULLETIN
- Accession number :
- edsair.doi...........8d4c019bf87ce54f54e8c08e746a7d2a