R-CHOP preceded by blood-brain barrier permeabilization (BBBp) by NGR-tumor necrosis factor (NGR-hTNF) in patients with relapsed or refractory primary CNS lymphoma (rrPCNSL): First results of the 'INGRID' phase II trial

7575Background: PCNSL pts are treated with HDMTX-based chemo, which requires hospitalization and extensive expertise to manage toxicity. R-CHOP could overcome these troubles, but CNS access of rela...