Back to Search
Start Over
Phthalimide-derived strigolactone mimics as germinating agents for seeds of parasitic weeds
- Source :
- Pest Management Science. 72:2069-2081
- Publication Year :
- 2016
- Publisher :
- Wiley, 2016.
-
Abstract
- Background Broomrapes attack important crops, cause severe yield losses and are difficult to eliminate because their seed bank is virtually indestructible. In the absence of a host, the induction of seed germination leads to inevitable death due to nutrient starvation. Synthetic analogues of germination-inducing factors may constitute a cheap and feasible strategy to control the seed bank. These compounds should be easy and cheap to synthesise, as this will allow their mass production. The aim of this work is to obtain new synthethic germinating agents. Results Nineteen N-substituted phthalimides containing a butenolide ring and different substituents in the aromatic ring were synthesised. The synthesis started with commercially available phthalimides. The complete collection was assayed against the parasitic weeds Orobanche minor, O. cumana, Phelipanche ramosa and P. aegyptiaca, with the synthetic strigolactone analogue GR24 used as a positive control. These compounds offered low EC50 values: O. cumana 38.3 μM, O. minor 3.77 μM, P. aegyptiaca 1.35 μM and P. ramosa 1.49 μM. Conclusions The synthesis was carried out in a few steps and provided the target compounds in good yields. The compounds tested showed great selectivity, and low EC50 values were obtained for structures that were simpler than GR24. © 2016 Society of Chemical Industry.
- Subjects :
- 0106 biological sciences
0301 basic medicine
2. Zero hunger
Phthalimides
biology
Strigolactone
General Medicine
biology.organism_classification
01 natural sciences
Phthalimide
03 medical and health sciences
Orobanche
chemistry.chemical_compound
030104 developmental biology
chemistry
Germination
Insect Science
Orobanche minor
Botany
Plant Weeds
Organic chemistry
Agronomy and Crop Science
010606 plant biology & botany
Butenolide
Subjects
Details
- ISSN :
- 1526498X
- Volume :
- 72
- Database :
- OpenAIRE
- Journal :
- Pest Management Science
- Accession number :
- edsair.doi...........8bb5538a031918a12da7e53ddaad4903