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Alcohols controlled selective radical cyclization of 1,6-dienes under mild conditions
- Source :
- Chinese Chemical Letters. 31:3267-3270
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- An efficient procedure for the selective preparation of hydroxy-, carbonyl- and acetal-containing 2-pyrrolidinones has been developed through radical cyclization of 1,6-dienes initiated by α-C(sp3)–H functionalization of alcohols. This protocol could be conducted at catalyst-free conditions at relatively low temperature (80 °C) by employing commercially available tert-butyl peroxybenzoate (TBPB) as the oxidant.
Details
- ISSN :
- 10018417
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Chinese Chemical Letters
- Accession number :
- edsair.doi...........8b11af3b93f1d189599b3dc4b7bc7dc6