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High Prevalence of bla CTX-M-1 Group Extended-Spectrum β-lactamase Genes in Escherichia coli Isolates From Tehran
- Source :
- Jundishapur Journal of Microbiology. 6
- Publication Year :
- 2013
- Publisher :
- Briefland, 2013.
-
Abstract
- and MIC. CTX-M encoding genes were identified by PCR, and blaCTX-M -carrying isolates were genotyped by rep-PCR. Results: A total of 140(70%) non-duplicate ESBL positive E. coli were determined. Imipenem and Amikacin were effective against 100% and 85% of all tested isolates respectively. Co-resistance of ESBL positive isolates to Erythromycin, Tetracycline, Co-trimoxazole and Ciprofloxacin were found in 93%, 75%, 63% and 43% of the strains, respectively. The rate of cefotaxime and ceftazidime resistant isolates dramatically decreased from 72% to 8.5% and 39% to 4.5% respectively, in the presence of clavulanic acid. Eighty nine (44.5%) E. coli isolates carried the blaCTX-M-1 group alleles. The levels of similarity of the rep-PCR fingerprints of blaCTX-M-1 isolates ranged from 40 to 90%. Conclusions: The rapid dissemination of non clonal multi-resistant CTX-M-1 producing E. coli isolates approved the need for further studies in our medical centers.
Details
- ISSN :
- 20084161 and 20083645
- Volume :
- 6
- Database :
- OpenAIRE
- Journal :
- Jundishapur Journal of Microbiology
- Accession number :
- edsair.doi...........8a61901225fc287fe70e1e75d4bf8df7
- Full Text :
- https://doi.org/10.5812/jjm.6863