High hepatic and plasma exposures of atorvastatin in subjects harboring impaired cytochrome P450 3A4∗16 modeled after virtual administrations and possibly associated with statin intolerance found in the Japanese adverse drug event report database

Subjects

Subjects :

Pharmacology
Pharmaceutical Science
Pharmacology (medical)

Details

ISSN :

13474367

Volume :

49

Database :

OpenAIRE

Journal :

Drug Metabolism and Pharmacokinetics

Accession number :

edsair.doi...........89f7a11a5420ca3beff9579938f0f98a

Full Text :

https://doi.org/10.1016/j.dmpk.2022.100486