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Real-Time Glucose Sensing Using a MEMS-Based Bi-Material Deflecting Membrane
- Source :
- ASME 2006 Frontiers in Biomedical Devices Conference.
- Publication Year :
- 2006
- Publisher :
- ASMEDC, 2006.
-
Abstract
- Self-monitoring of blood glucose has become an important and critical tool for effective management of diabetes. A closed-loop, real-time sensing and dispensing system, however, has been elusive. We describe here, a novel MEMS-based sensor intended to measure, in realtime, the concentration of glucose in a solution. The device utilizes a bi-material membrane with a functional hydrogel layer that swells reversibly, and in proportion to, the presence of glucose. The hydrogel is composed of 2-hydroxyethyl methacrylate (HEMA) functionalized with 3-acrylamidophenylboronic acid (AAPBA) groups as the glucose-sensitive moiety. Phenylboronic acid (PBA) derivatives interact with glucose by forming a charged complex, causing the hydrogel to swell by solvent intake [1].Copyright © 2006 by ASME
Details
- Database :
- OpenAIRE
- Journal :
- ASME 2006 Frontiers in Biomedical Devices Conference
- Accession number :
- edsair.doi...........8953ceee0990cc1a4ff19b2e2826cb4f