Synthetic Studies on Arglabin Diene; An Alleged Precursor to Arteminolides

E-mail: sohnjh@cnu.ac.krReceived October 31, 2011, Accepted November 1, 2011Key Words : Arteminolide, Santonin, Farnesyltransferase, Photochemical rearrangementArteminolides A-D (1-4), isolated from the leaves ofArtemisia sylvatica Maxim, are triterpene lactones (Figure1) and have been reported to be strong inhibitors offarnesyltransferase (FTase).