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ChemInform Abstract: Preparation of New 5-Aroylamino Substituted 3-Nicotinoyl/Isonicotinoyl-1,3,4-thiadiazol-2(3H)-ones with Anti-inflammatory Activity
- Source :
- ChemInform. 30
- Publication Year :
- 2010
- Publisher :
- Wiley, 2010.
-
Abstract
- A series of 1,3,4-thiadiazol-2(3H)-ones (2a–j) with a nicotinoyl/isonicotinoyl group in position 3 and an aroylamino substituent in position 5 of the ring was prepared and evaluated for antipyretic and anti-inflammatory activities. All the title compounds and in particular 2e, 2i and 2j exhibited anti-inflammatory activity and were devoid of antipyretic properties.
Details
- ISSN :
- 15222667 and 09317597
- Volume :
- 30
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........88979a746916c1537c20d2935a529f7c