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A facile synthesis of (2S,3R,4S)-4-amino-5-cyclohexyl-1-morpholino-2,3-pentanediol, the C-terminal compound of renin inhibitor BW-175

Authors :
Guo-Qiang Lin
Zhi-cai Shi
Source :
Tetrahedron. 51:2427-2434
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

A facile synthesis of (2 S , 3 R , 4 S )-4-amino-5-cyclohexyl-1-morpholino-2, pentanediol (ACMP), the C-terminal compounds of renin inhibitor BW-175 is described.

Details

ISSN :
00404020
Volume :
51
Database :
OpenAIRE
Journal :
Tetrahedron
Accession number :
edsair.doi...........87f24ffeafce710b8657df967e8d9604
Full Text :
https://doi.org/10.1016/0040-4020(94)01107-b