Inhibition of Proprotein Convertase Subtilisin/Kexin type 9 (PCSK9) secretion by prodomain overexpression or pefabloc treatment as measured by a luciferase assay

Authors :: Michel Perez
Claudie Cathala
Céline Robichon
Didier Cussac
Luc De Vries
Didier Junquero
Source :: The FASEB Journal. 24
Publication Year :: 2010
Publisher :: Wiley, 2010.
Abstract: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a secreted protease that acts as a regulator of circulating plasma cholesterol levels by enhancing the endocytosis of the low density lipopr...

Subjects :: animal structures
Protease
Chemistry
medicine.medical_treatment
PCSK9
fungi
Subtilisin
Proprotein convertase
Endocytosis
Biochemistry
Cell biology
Genetics
medicine
Kexin
Luciferase
Secretion
Molecular Biology
Biotechnology

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