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Synthesis of monooleoyl glycerophospho heptapeptide as a candidate of pathogen of essential hypertension

Authors :
Tetsuo Shiba
Kaoru Inami
Source :
Bioorganic & Medicinal Chemistry Letters. 6:601-604
Publication Year :
1996
Publisher :
Elsevier BV, 1996.

Abstract

A monooleoyl glycerophospho heptapeptide was synthesized as a candidate of the endogenous pathogen of essential hypertension. Synthesis of the target compound was achieved by the fragment condensation of the phosphorylated tetrapeptide with a His-containing tripeptide.

Details

ISSN :
0960894X
Volume :
6
Database :
OpenAIRE
Journal :
Bioorganic & Medicinal Chemistry Letters
Accession number :
edsair.doi...........87d07d946c18a3a1e311287cc6f8d031
Full Text :
https://doi.org/10.1016/0960-894x(96)00080-7