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Comparison of the effectiveness of Ankaferd Blood Stopper ® and Emdogain in periodontal regeneration
- Source :
- Oral Diseases. 28:1947-1957
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- OBJECTIVES The present study was performed to compare the effectiveness of Ankaferd Blood Stopper® (ABS) with enamel matrix derivatives (EMD) for treating fenestration defects in rats. MATERIALS AND METHODS Forty-eight male Wistar rats were randomly divided into six groups (each n = 8). Fenestration defects were created in all rats, to which ABS, EMD, or saline (S) was then applied. The rats were grouped and sacrificed at one of two different time points, as follows: ABS-10-group, ABS-treatment/sacrifice on day 10; EMD-10-group, EMD-treatment/sacrifice on day 10; S-10-group, S-treatment/sacrifice on day 10; ABS-38-group, ABS-treatment/sacrifice on day 38; EMD-38-group, EMD-treatment/sacrifice on day 38; and S-38-group, S-treatment/sacrifice on day 38. Then, histomorphometric analysis including measurements of new bone area (NBA) and new bone ratio (NBR), and immunohistochemical analysis including the determination of osteopontin (OPN) and type-III-collagen (C-III) expression were performed. RESULTS The NBA and NBR were significantly higher in the ABS-10-group and EMD-10-group compared to the S-10-group (p
- Subjects :
- Type III collagen
medicine.medical_specialty
biology
business.industry
Regeneration (biology)
medicine.medical_treatment
Urology
030206 dentistry
Bone area
03 medical and health sciences
0302 clinical medicine
Otorhinolaryngology
030220 oncology & carcinogenesis
biology.protein
Medicine
Osteopontin
business
Fenestration
General Dentistry
Saline
Ankaferd blood stopper
Subjects
Details
- ISSN :
- 16010825 and 1354523X
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Oral Diseases
- Accession number :
- edsair.doi...........868752adf200b9ca40a9942e0a99dbf4