Detection of Carbapenemase Resistance among Clinical Isolates of Escherichia coli

Carbapenems have been among the most powerful antibiotics for treating serious infections caused by Gram-negative pathogens, which includes Enterobactericeae, Pseudomonas aeruginosa and Acinetobacter baumannii. We have screened for the antibiotic sensitivity pattern followed by the detection of carbapenemase in our isolates. We found a higher percentage of isolates were shown to be resistant to multiple antibiotics and confirmed to be an multiple drug resistant strains, 15% of isolates were carbapenemase producers. Its ideal to include this test in routine sensitivity pattern in order to rule out the actul mechanism and prompt theapy.