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ChemInform Abstract: AROMATIZATION AND MICROBIAL HYDROXYLATION OF 3-18O-TESTOSTERONE

Authors :
Gregg J. Taylor
Herbert L. Holland
Source :
Chemischer Informationsdienst. 12
Publication Year :
1981
Publisher :
Wiley, 1981.

Abstract

3-18O-Testosterone (1) is transformed to estradiol (4) by human placental microsomes, and to the 6β- and 11α-hydroxy derivatives 2 and 3 by Rhizopusarrhizus, without significant loss of label. Neither process is therefore one which involves reversible Schiff base formation at C-3 at any stage.

Details

ISSN :
00092975
Volume :
12
Database :
OpenAIRE
Journal :
Chemischer Informationsdienst
Accession number :
edsair.doi...........84c831e7120ec50b2bc6995af8a2c01e
Full Text :
https://doi.org/10.1002/chin.198115154