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Evaluation of matrix solid-phase dispersion extraction for 11 β-agonists in swine feed by liquid chromatography with electrospray ionization tandem mass spectrometry
- Source :
- Journal of Separation Science. 37:2574-2582
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- A sensitive liquid chromatography with tandem mass spectrometry method was developed for the determination of 11 β-agonists (clenbuterol, salbutamol, ractopamine, terbutaline, fenoterol, cimaterol, isoxsuprine, mabuterol, mapenterol, clenproperol, and tulobuterol) in swine feed. This rapid, simple, and effective extraction method was based on matrix solid-phase dispersion. The limit of quantification of clenbuterol, cimaterol, mabuterol, salbutamol, terbutaline, mapenterol, clenproperol, and tulobuterol was 1 μg/kg and that of ractopamine, fenoterol, and isoxsuprine was 2 μg/kg. The recoveries of β-agonists spiked in swine feeds at a concentration range of 1-8 μg/kg were >83.1% with relative standard deviations
Details
- ISSN :
- 16159306
- Volume :
- 37
- Database :
- OpenAIRE
- Journal :
- Journal of Separation Science
- Accession number :
- edsair.doi...........847bb27e0b1f5a05c29c96fa72f4f50f