Back to Search
Start Over
Flow-controlled synthesis of gold nanoparticles in a biphasic system with inline liquid–liquid separation
- Source :
- Reaction Chemistry & Engineering. 5:356-366
- Publication Year :
- 2020
- Publisher :
- Royal Society of Chemistry (RSC), 2020.
-
Abstract
- We present the flow synthesis of 4-(dimethylamino)pyridine (DMAP)-stabilised gold nanoparticles in a biphasic flow reactor system. In the first stage, the reduction of gold chloride using sodium borohydride took place via gas permeable tubing to minimise pressure build-up in the lines due to hydrogen gas liberation. The use of liquid–liquid membrane separators enabled automatic washing of the intermediate tetraoctylammonium bromide (TOAB)-stabilised gold nanoparticles and for subsequent phase transfer of the organic nanoparticles to the aqueous phase using DMAP. Through a systematic investigation of DMAP concentration and ratio, the amount of DMAP necessary for full transfer of the gold nanoparticles was elucidated. This semi-automated, scalable flow process enabled the production of gold nanoparticles in high yield, with good batch-to-batch reproducibility and improved monodispersity compared to conventional batch methods.
- Subjects :
- Fluid Flow and Transfer Processes
Materials science
Process Chemistry and Technology
Aqueous two-phase system
Nanoparticle
02 engineering and technology
010402 general chemistry
021001 nanoscience & nanotechnology
01 natural sciences
Catalysis
0104 chemical sciences
Nanomaterials
chemistry.chemical_compound
Sodium borohydride
Membrane
Chemical engineering
chemistry
Chemistry (miscellaneous)
Colloidal gold
Phase (matter)
Chemical Engineering (miscellaneous)
Tetraoctylammonium bromide
0210 nano-technology
Subjects
Details
- ISSN :
- 20589883
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Reaction Chemistry & Engineering
- Accession number :
- edsair.doi...........840c8f7371faa0a58db8a3061c25cf8d