ChemInform Abstract: Palladium-Catalyzed Decarboxylative C3-Acylation of Benzofurans and Benzothiophenes with α-Oxocarboxylic Acids via Direct sp2C-H Bond Activation

An efficient approach to decarboxylative C3-acylation of benzothiophenes or benzofurans with α-oxocarboxylic acids via palladium-catalyzed C–H bond activation was developed. This method was compatible with a variety of functional groups and provided an attractive route to 3-acylbenzothiophenes and 3-acylbenzofurans in good to high yields.