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Testiculotoxicity activities of Isopropyl Alcohol-based Air Freshener on the Testis of Adult Wistar Rats

Authors :
Akihoromotei Idhirhi
A.O. Ojewale
Stephen okikioluwa Adeyelu
Oluwaseun Ruth Olasehinde
Akingbade Am
Oluwaseun Babatunde Ibitoye
Source :
Journal of Molecular Pathophysiology. 6:17
Publication Year :
2017
Publisher :
ScopeMed, 2017.

Abstract

Background/Aim: The effects of several household materials containing toxic chemicals have been a focus point in recent studies concerning male infertility. In this study, we evaluated the testiculotoxic effect of isopropyl alcohol-based air freshener (IBA) on the testis of adult wistar rats. Materials and Methods: Twenty adult wistar rats were divided at random, to four groups, five in each group. Group A rats were exposed to natural air for 4 weeks. The study groups (B, C and D) were exposed to different graded doses of IBA for 4 weeks. Group B rats were exposed to 2.5ml, group C to 5ml and group D to 10 ml of IBA for 6hrs/day via whole body inhalation. Results: The results of the study showed a statistically significant (p

Details

ISSN :
2146832X
Volume :
6
Database :
OpenAIRE
Journal :
Journal of Molecular Pathophysiology
Accession number :
edsair.doi...........837bb6475af30fc2e233ed68275294a6