Troubleshooting When Using γ-Valerolactone (GVL) in Green Solid-Phase Peptide Synthesis

Authors :: Adeniyi Thompson-Adewumi
Fernando Albericio
K. P. Nandhini
Ashok Kumar
Beatriz G. de la Torre
Jonathan M. Collins
Source :: Organic Process Research & Development. 23:1096-1100
Publication Year :: 2019
Publisher :: American Chemical Society (ACS), 2019.
Abstract: The synthesis of peptides for both research and API production is conveniently carried out using the solid-phase strategy. However, the main drawback of this approach is the large amounts of hazard...

Subjects :: Valerolactone
chemistry.chemical_compound
010405 organic chemistry
Chemistry
Organic Chemistry
Peptide synthesis
Troubleshooting
Physical and Theoretical Chemistry
010402 general chemistry
01 natural sciences
Combinatorial chemistry
0104 chemical sciences

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